Safety Evaluation of the Polyherbal Formulation NawaTab: Acute and Subacute Oral Toxicity Studies in Rats

Table 1

Body weight gain and food and water consumption of NawaTab-treated rats in the subacute toxicity study.

Parameters	Control	NawaTab (mg/kg BW)
		250	500	1000
Males
Body weight gain (%)	117.8 ± 4.0	125.0 ± 3.0	117.5 ± 5.5	114.4 ± 3.5
Food consumption (g/day)	20.0 ± 0.4	20.8 ± 0.4	20.0 ± 0.5	20.0 ± 0.4
Water consumption (ml/day)	25.9 ± 0.7	27.7 ± 0.7	28.6 ± 0.7	26.2 ± 0.6
Females
Body weight gain (%)	49.1 ± 3.7	52.6 ± 6.1	46.5 ± 3.7	57.2 ± 3.8
Food consumption (g/day)	14.6 ± 0.3	15.8 ± 0.4	14.7 ± 0.5	14.1 ± 0.7
Water consumption (ml/day)	25.4 ± 0.5	29.6 ± 0.6	29.8 ± 0.9	31.1 ± 0.9

Data are expressed as the mean ± S.E.M., n = 5 animals/sex/group. , significantly different from the control group.