Safety Evaluation of the Polyherbal Formulation NawaTab: Acute and Subacute Oral Toxicity Studies in Rats

Table 4

Relative organ weight (g/100 g BW) of NawaTab-treated rats in the subacute toxicity study.

Parameters	Control	NawaTab (mg/kg BW)
		250	500	1000
Males
Thymus gland	0.20 ± 0.02	0.20 ± 0.02	0.18 ± 0.02	0.20 ± 0.02
Heart	0.30 ± 0.01	0.30 ± 0.00	0.31 ± 0.01	0.30 ± 0.00
Lung	0.38 ± 0.01	0.41 ± 0.01	0.41 ± 0.01	0.40 ± 0.01
Liver	3.41 ± 0.03	3.50 ± 0.11	3.50 ± 0.09	3.35 ± 0.10
Kidney	0.78 ± 0.02	0.80 ± 0.01	0.80 ± 0.01	0.79 ± 0.03
Spleen	0.21 ± 0.01	0.20 ± 0.01	0.20 ± 0.03	0.23 ± 0.01
Testis	1.03 ± 0.02	1.07 ± 0.03	1.13 ± 0.03	1.10 ± 0.03
Prostate gland	0.23 ± 0.01	0.21 ± 0.01	0.21 ± 0.01	0.21 ± 0.02
Epididymis	0.21 ± 0.02	0.22 ± 0.01	0.24 ± 0.00	0.24 ± 0.01
Vas deferens	0.05 ± 0.00	0.05 ± 0.00	0.05 ± 0.00	0.05 ± 0.00
Females
Thymus gland	0.21 ± 0.01	0.22 ± 0.01	0.21 ± 0.01	0.22 ± 0.02
Heart	0.31 ± 0.01	0.32 ± 0.00	0.32 ± 0.01	0.32 ± 0.01
Lung	0.45 ± 0.01	0.46 ± 0.02	0.50 ± 0.05	0.43 ± 0.01
Liver	3.49 ± 0.07	3.66 ± 0.14	3.45 ± 0.07	3.64 ± 0.06
Kidney	0.83 ± 0.02	0.83 ± 0.04	0.83 ± 0.02	0.80 ± 0.02
Spleen	0.23 ± 0.01	0.24 ± 0.01	0.25 ± 0.01	0.23 ± 0.01
Ovary	0.06 ± 0.00	0.07 ± 0.01	0.07 ± 0.00	0.06 ± 0.00
Uterus	0.23 ± 0.04	0.22 ± 0.01	0.30 ± 0.05	0.30 ± 0.06

Data are expressed as the mean ± S.E.M., n = 5 animals/sex/group.