Melatonin-Attenuated Oxidative Stress in High-Risk Pregnant Women Receiving Enoxaparin and Aspirin

Table 1

Comparison of changes in the oxidative stress and inflammatory biomarkers for study between the intervention and control groups.

Variable	Groups	Baseline	After	value	Difference (baseline-after)	value
TAC (μmol/L)	Control	663.25 ± 230.36	552.16 ± 135.20	0.036	4.25 ± 553.81	0.008
	Intervention	527.75 ± 142.79	643.34 ± 190.49	0.064	−170.12 ± 322.01
MDA (μmol/L)	Control	1161.86 ± 195.19	1020.83 ± 130.33	0.043	141.02 ± 290.22	0.396
	Intervention	1179.17 ± 248.04	1125.32 ± 240.10	0.498	53.85 ± 348.80
T-SH (μmol/L)	Control	9.96 ± 3.03	6.18 ± 1.67	<0.001	3.78 ± 2.67	0.017
	Intervention	10.55 ± 4.02	18.27 ± 30.00	0.658	−7.71 ± 29.39
NO (μmol/L)	Control	3.13 ± 2.62	2.76 ± 2.70	0.668	0.37 ± 3.78	0.034
	Intervention	4.38 ± 3.84	1.16 ± 1.39	0.004	3.22 ± 4.30
PCO (μmol/L)	Control	21.10 ± 6.07	6.55 ± 6.66	<0.001	14.55 ± 7.07	<0.001
	Intervention	13.99 ± 6.41	11.51 ± 5.15	0.221	2.47 ± 8.51
hs-CRP (μg/mL)	Control	12.47 ± 9.82	6.40 ± 3.70	0.067	6.07 ± 11.85	0.278
	Intervention	12.85 ± 9.67	4.38 ± 0.87	0.002	8.46 ± 9.46

TAC, total antioxidant capacity; MDA, malondialdehyde; T-SH, sulfhydryl protein; NO, nitric oxide; PCO, protein carbonyl; hs-CRP, high-sensitivity C-reactive protein.