An Updated Comprehensive Review of Plants and Herbal Compounds with Antiasthmatic Effect

Table 1

The plants or herbal compounds that have shown antiasthmatic effects in clinical studies and their mechanism of action.

Plants or compound	Effect on airways	Effect on pulmonary function tests	Reference(s)
No.3.1.6 Argemone mexicana	Inhibiting bronchospasm		[27]
No.3.3.1 Baicalin	↓ AHR, improving airway resistance and lung compliance		[28, 29]
No.3.1.8 Biophytum sensitivum	Inhibiting histamine-induced bronchoconstriction		[30]
No.3.1.9 Boswellia serrata		↑ FEV1, FVC, PEFR; ↓ Episodes of asthmatic attacks	[31, 32]
No.3.1.13 Carum copticum	Bronchodilator effect	↑ FEV1, PEF, MMEF, MEF75, MEF50, MEF25, and sGaw	[33]
No.3.3.3 Carvacrol	↓ AHR	↑FEV1, FVC, MMEF, PEF, MEF75, MEF50, and MEF25	[34–36]
No.3.1.15 Crataegus pinnatifida	↓ AHR		[37]
No.3.1.16 Crocus sativus	↓ AHR		[38, 39]
No.3.1.17 Curcuma longa rhizome (curcumin)	↓ AHR		[40]
No.3.3.9 Gallic acid	↓ AHR		[41]
No.3.1.25 Ginkgo biloba		Improved FEV1/FVC	[42]
No.3.1.26 Glycirizine glabra	↓ AHR	Improved FVC and FEV1, ↓ PIF, PEF, TV, and EV	[43]
No.3.1.27 Hedera helix	↓ Airway resistance		[44]
No.3.3.11 Hesperetin	↓ AHR		[45]
No.3.1.36 Moringa oleifera		Improvement of FVC, FEV1, FEV1/FVC, PEFR, FEF 25–75%, and MVV	[46]
No.3.3.22 Naringenine	↓ AHR		[47]
No.3.1.37 Nigella sativa		↑ FVC, FEV1, MMEF, MEF50, MEF75, and MEF25	[48, 49]
No.3.2.43 Pimpinella anisum	Bronchodilator activity		[50]

The number in the first column refers to the paragraph in the text describing the plant/compound characteristics.