Antiplatelet and Antithrombotic Activities of <i>Lespedeza cuneata</i> via Pharmacological Inhibition of Integrin <i>α</i>IIb<i>β</i>3, MAPK, and PI3K/AKT Pathways and FeCl3-Induced Murine Thrombosis

<div>Gas chromatography-mass spectrometry analysis. To separate and measure <i>Lespedeza cuneata</i> compounds, the GC-MS instrument was outfitted with a 30 m × 0.25 mm (i.d. DB-5MS) chromatography column and an Agilent 5975C mass selective detector. At 250°C, the extract was injected. The source and transfer lines had temperatures of 230°C and 280°C, respectively. The column temperature was initially set at 70°C for 1 min and then increased to 300°C at a rate of 5°C/min, remaining at this ultimate temperature for 30 min. Scan and electron ionization modes were used to obtain mass spectrometry data.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1

Figure 1: Antiplatelet and Antithrombotic Activities of <i>Lespedeza cuneata</i> via Pharmacological Inhibition of Integrin <i>α</i>IIb<i>β</i>3, MAPK, and PI3K/AKT Pathways and FeCl3-Induced Murine Thrombosis 

Figure 1 | Antiplatelet and Antithrombotic Activities of Lespedeza cuneata via Pharmacological Inhibition of Integrin αIIbβ3, MAPK, and PI3K/AKT Pathways and FeCl3-Induced Murine Thrombosis 