Multimodal Exercise in Older Patients with Advanced Pancreatic Cancer Undergoing First-Line Chemotherapy: A Case Series Examining Feasibility and Preliminary Efficacy

Table 1

Baseline characteristics of enrolled patients.

Variables	Case #1	Case #2	Case #3	Case #4	Case #5	Case #6
Age (years)	73	60	66	63	72	75
Gender	Male	Male	Male	Male	Male	Female
BMI (kg/m^2)	26.9	26.7	30.8	22.4	18.8	23.6
Marital status	Divorced	Married	Married	Divorced	Married	Divorced
Education level	Bachelor’s degree	Higher degree	Higher degree	Bachelor’s degree	Bachelor’s degree	Not disclosed
Employment status	Part-time	Full-time	Retired	Retired	Retired	Full-time
Cigarette smoking	Never	Never	Past	Never	Never	Past
Current drinker	No	No	Yes	No	Yes	No
Godin leisure score index^a	16	0	3	9	Unknown	15
Clinical stage	Metastatic (liver)	Metastatic (liver)	Locally advanced	Metastatic (liver)^b	Metastatic (lung)^b	Locally advanced
TNM classification	T2N2M1	T4N2M1	T1bN0M0	T3bN1M0^c	T3N1M0^c	T4N1M0
Time since diagnosis (weeks)	33	23	13	4^d	23^d	3
Tumor histology	Adenocarcinoma	Adenocarcinoma	Adenocarcinoma	Adenocarcinoma	Adenocarcinoma	Adenocarcinoma
Primary tumor location	Tail of the pancreas	Head of the pancreas	Head of the pancreas	Ampulla of vater	Head of the pancreas	Body of the pancreas
Time since starting first-line therapy (weeks)	29	20	10	3^e	0	0
Comorbid conditions
Hypertension	No	No	Yes	Yes	Yes	Yes
High cholesterol	No	No	Yes	No	Yes	Yes
Heart disease	No	No	Yes	No	No	No
Diabetes	No	No	No	Yes	No	Yes
Parkinson’s disease	No	No	No	Yes	No	No

^aA Godin leisure score index of 14–23 units or less than 14 units is classified as moderate active or insufficient active [40]. ^bDistant relapse from the pancreatic primary. ^cAt the time of the initial diagnosis. ^dTime since diagnosis of recurrent metastases. ^eTime since starting the initial chemotherapy for recurrent metastases. BMI, body mass index.