Research Article
Primary Angiosarcoma of the Breast: A 20-Year Single-Institution Experience in China
Table 3
Clinicopathological findings in 12 patients with follow-up data.
| | Case No | Age (years) | Side | Color | Texture | Nipple retraction | Hydrod-erma | Tumor size (CM) | Type of surgery | Surgical margin | Tumor grade | Immunohist-Ochemical markers | Lymph node | Adjuvant therapy | Follow-up (months) |
| | 1 | 16 | R | Purple | Soft | No | No | 11 | MRM | R1 | II | CD31, CD34, ki-67 30% | 0/29 | No | 7 | | 2 | 47 | R | UK | UK | No | Yes | 1.3 | MRM | R0 | UK | CD34 | 0/23 | Chemo | 114 | | 3 | 57 | L | UK | Hard | No | No | 2.4 | MRM | R0 | I | UK | 0/23 | Chemo | 88.3 | | 4 | 30 | L | Red | Soft | Yes | Yes | 7 | MRM | R0 | II-III | UK | 0/19 | Chemo | 54 | | 5 | 16 | L | Red | Cystic | Yes | Yes | 8 | Mastectomy + SNLB + LDMF | R1 | III | CD31, CD34, ki-67 30–60% | 0/4 | Chemo + Radio | 36 | | 6 | 48 | L | UK | Hard | No | No | 2.5 | MRM | R0 | I-II | UK | 0/10 | Chemo | 85 | | 7 | 16 | L | Blue | Hard | No | No | 6 | MRM | R0 | I-II | CD31, CD34, KI-67 70% | UK | Chemo | 85 | | 8 | 31 | R | Purple | Cystic | Yes | Yes | 17 | Mastectomy and skin-grafting | R0 | III | CD31, CD34, ki-67 50% | UP | Chemo | 3 (contralateral breast relapse) | | 9 | 60 | L | UK | Hard | No | No | 2.4 | MRM | R0 | I | UK | 0/22 | No | 32 (death) | | 10 | 18 | R | UK | Cystic | No | No | 6 | Breast tumor resection | UK | II | CD31, CD34, ki-67 40% | UP | Chemo | 6 (ipsilateral breast and lung metastasis) | | 11 | 60 | L | UK | Hard | No | No | 5 | Mastectomy + SNLB | UK | III | UK | 0/4 | Chemo | 1 (lung and bone metastasis) | | 12 | 54 | L | UK | Hard | No | No | 7 | Mastectomy | R0 | II | CD31, CD34, ki-67 < 5% | 0/13 | Chemo + Radio | 44 (death) |
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L, left; R, right; MRM, modified radical mastectomy; SLNB, sentinel lymph node biopsy; LDMF, latissimus dorsi myocutaneous flap; Chemo, chemotherapy; Radio, radiotherapy; UK, unknown; UP, unperformed.
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