Impact of Early Chemotherapy Resumption on the Outcome after Staphylococcus aureus Bacteremia in Patients with Solid Tumors: A Retrospective Study in a Single Tertiary Cancer Center in Japan
Table 2
Characteristics of the patients among early and late resumption of chemotherapy.
Characteristics
Early or late chemotherapy resumption
value
Early ≦17.5 days (n = 18)
Late >17.5 days (n = 18)
Age, median (range)
58.0 (28–71)
67.0 (44–78)
0.048
Sex (male), n (%)
10 (56)
10 (56)
1.000
ECOG-PS, n (%)
0.658
0-1
14 (78)
16 (89)
2–4
4 (22)
2 (11)
Cancer type, n (%)
Gastrointestinal cancers
11 (61)
12 (67)
1.000
Thoracic cancers
2 (11)
0 (0)
0.243
Breast cancers
4 (22)
1 (6)
0.338
Others
1 (6)
5 (27)
0.177
Cancer status, n (%)
0.177
Metastatic
17 (94)
13 (72)
Nonmetastatic
1 (6)
5 (28)
Chemotherapy line, median (range)
1 (1–11)
1.5 (1–5)
0.505
Chemotherapy
1.000
Cytotoxic agents
18 (100)
17 (94)
Targeted agents
0 (0)
1 (6)
Source of infection, n (%)
CRBSI
16 (88)
11 (61)
0.121
Skin and soft tissue
1 (6)
3 (16)
0.353
Pneumonia
0 (0)
1 (6)
1.000
Unknown origin
1 (6)
1 (6)
1.000
Others
0 (0)
2 (11)
0.486
MRSA, n (%)
2 (11)
3 (16)
1.000
ID consultation, n (%)
18 (100)
18 (100)
1.000
Pitt bacteremia score, median (range)
0 (0–4)
1 (0–3)
0.453
Serum albumin, median (range)
3.25 (2.0–5.0)
2.9 (1.7–4.2)
0.346
Days from negative blood culture to chemotherapy resumption, median (range)