Identification of a Novel Circadian Rhythm-Related Signature for Predicting Prognosis and Therapies in Hepatocellular Carcinoma Based on Bulk and Single-Cell RNA Sequencing

<div>High-CR score correlated with poor survival of HCC patients. (a) The volcano plot of DEGs between tumor and normal samples of HCCs in the TCGA-LIHC cohort. (b) Heatmap of DEGs between tumor and normal samples of HCCs in the TCGA-LIHC cohort. (c) Venn plot of the differentially expressed CRRGs by overlapping DEGs and CRRGs. (d) Heatmap of 40 intersected CRRGs between tumor and normal samples of HCCs in the TCGA-LIHC cohort. (e) Kaplan–Meier plots for HCCs in high-CR score and low-CR score groups.</div>

European Journal of Cancer Care

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Figure 1: Identification of a Novel Circadian Rhythm-Related Signature for Predicting Prognosis and Therapies in Hepatocellular Carcinoma Based on Bulk and Single-Cell RNA Sequencing 

Figure 1 | Identification of a Novel Circadian Rhythm-Related Signature for Predicting Prognosis and Therapies in Hepatocellular Carcinoma Based on Bulk and Single-Cell RNA Sequencing 