Exploring Cinnamic Acids as Potent Antimetastatic Agents for Cancer Therapy: Molecular Docking and Dynamic Simulation against MMP2

Figure 3

The impact of free MMP2 backbone atoms during a 100 ns MD simulation was studied with a focus on (a) RMSF and (b) RMSD to examine the influence of cynarin and oleandrin. The asterisks in the RMSF plots denote the active site of the receptor. MMP2, matrix metalloproteinase 2; RMSF, root mean square fluctuation; RMSD, root mean square deviations.

(a)

(b)