Exploring Cinnamic Acids as Potent Antimetastatic Agents for Cancer Therapy: Molecular Docking and Dynamic Simulation against MMP2

Figure 4

The study investigated the impact of free MMP2 backbone atoms during a 100 ns MD simulation, with a specific emphasis on (a) ROG and (b) total energy plots. The objective was to scrutinize the influence of cynarin and oleandrin on these two parameters. MMP2, matrix metalloproteinase 2; MD, molecular dynamics; ROG, radius of gyration.

(a)

(b)