Research Article
Anticolorectal Cancer Activity of Bilobalide in Patient-Derived Colorectal Cancer Organoids and AOM/DSS Mouse Model
Figure 4
Bilobalide enhanced the apoptosis of the CRC organoids by inhibiting the polarization of M2 macrophages. (a) The concentration of IL-10 and TNF-α in the supernatants, compared with the M2 group. (b) Relative expression of apoptosis-associated proteins, , the Bil + M2 group compared with the blank group, , ##, and Δ compared with β-actin. (c) TUNEL staining.
(a) |
(b) |
(c) |