Anticolorectal Cancer Activity of Bilobalide in Patient-Derived Colorectal Cancer Organoids and AOM/DSS Mouse Model

<div>Bilobalide prevented intestinal tumorigenesis in mice. (a) Schematic representation for the establishment of the AOM/DSS mice model. (b) Changes in the body weights of mice from the control, model, 2.5 mg/kg bilobalide, and 5 mg/kg bilobalide groups. (c) Survival rates of mice from the control, model, 2.5 mg/kg bilobalide, and 5 mg/kg bilobalide groups. (d-f) Change in the tumor number, tumor size and incidence. (g) Change in the length and morphology of the colon. (e) Change in the length and morphology of the colon. (h) Effect of bilobalide on histological alteration. 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European Journal of Cancer Care

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Figure 5

Figure 5: Anticolorectal Cancer Activity of Bilobalide in Patient-Derived Colorectal Cancer Organoids and AOM/DSS Mouse Model 