Anticolorectal Cancer Activity of Bilobalide in Patient-Derived Colorectal Cancer Organoids and AOM/DSS Mouse Model

Table 2

The treatment schedule of AOM/DSS mice.

Groups (n = 10)	Time (d)
	1–7	8–14	15–28	29–35	36–49	50–56	57–79	80
Control	Normal saline	Water						Sacrifice
AOM/DSS	AOM (7.5 mg/kg, i.p.)	DSS (2.5%)	Water	DSS (2.5%)	Water	DSS (2.5%)	Water
Bilobalide (2.5 mg/kg)		DSS (2.5%)	Water	DSS (2.5%)	Water	DSS (2.5%)	Water
		Bilobalide (2.5 mg/kg, i.g.)
Bilobalide (5.0 mg/kg)		DSS (2.5%)	Water	DSS (2.5%)	Water	DSS (2.5%)	Water
		Bilobalide (5.0 mg/kg, i.g.)