Prone versus Supine Position Ventilation in Adult Patients with Acute Respiratory Distress Syndrome: A Meta-Analysis of Randomized Controlled Trials

Table 1

Baseline characteristics of the included studies.

Study	Country	Sample size	Mean age (years)	Percentage male (%)	Mean PaO2: FIO2	Mean PEEP (cm H2O)	Mean FIO2 (%)	Duration of ARDS	Duration of prone positioning	Protective lung ventilation	Jadad scale
Gattinoni et al. [22]	Italy and Switzerland	304	58.0	70.4	125/130	9.0	73.0	NA	7 hours daily for 4.7 days	No	6
Beuret et al. [23]	France	51	55.0	70.6	315/337	NA	NA	<24.0 hours	4 hours daily for 6.0 days	No	5
Watanabe et al. [24]	Japan	16	64.5	87.5	166/NA	NA	NA	NA	6 hours daily for 4.0 days	No	3
Guérin et al. [25]	France	791	62.2	75.0	150/155	8.0	66.0	12.0–24.0 hours	9 hours daily for 4.1 days	No	5
Papazian et al. [26]	France	26	53.0	65.4	101/106	11.5	71.5	<24.0 hours	12 hours daily for 1.0 day	No	2
Voggenreiter et al. [27]	Germany	40	41.4	82.5	215/228	11.5	49.0	<48.0 hours	11 hours daily for 7.0 day	Yes	5
Mancebo et al. [28]	Spain and Mexico	136	54.0	63.2	132/161	7.0	82.0	<48.0 hours	17 hours daily for 10.1 day	No	4
Demory et al. [29]	France	30	54.0	73.3	122.0	11.0	NA	<24.0 hours	12 hours daily for 1.0 day	Yes	4
Chan et al. [30]	Taiwan	22	62.3	81.8	111/108	13.3	87.5	<72.0 hours	24 hours daily for 4.4 day	Yes	4
Fernandez et al. [31]	Spain	40	54.6	37.5	114/122	11.2	84.5	<48.0 hours	18 hours daily for first 2 days	Yes	5
Taccone et al. [32]	Italy and Spain	342	60.0	71.3	113.0	10.0	72.0	<72.0 hours	18 hours daily for first 8.3 days	Yes	5
Guérin et al. [33]	France and Spain	466	59.0	68.2	100/100	10.0	79.0	<36.0 hours	17 hours daily for first 4.0 days	Yes	6

Both group; ARDS: acute respiratory distress syndrome; FIO₂: fractional concentration of inspired oxygen; NA: not available; PaO₂: partial pressure of arterial oxygen; PEEP: positive end-expiratory pressure.