Prognostic Utility of the Combination of Platelet Count with Neutrophil-to-Lymphocyte Ratio in Aged Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention

Table 3

Predictors of in-hospital mortality in univariable and multivariable Cox regression analyses.

Variables	Univariable			Multivariable
	HR	95% CI		HR	95% CI
Age	1.026	0.975–1.079	0.331
Gender (male)	1.457	0.838–2.533	0.182
Gensini score	1.007	1.002–1.011	0.005	NS	NS	NS
Killip class	2.282	1.779–2.927	<0.001	1.810	1.367–2.397	<0.001
LVEF	0.954	0.935–0.974	<0.001	0.978	0.957–0.999	0.040
Smoke and drink	1.521	0.832–2.779	0.173
Hypertension	1.075	0.615–1.878	0.800
Prior CHD	2.274	1.192–4.338	0.013	2.195	1.130–4.264	0.020
Diabetes	1.106	0.618–1.979	0.734
Total cholesterol	0.834	0.649–1.070	0.153
Total triglyceride	0.932	0.691–1.255	0.641
HDL	0.318	0.115–0.877	0.027	0.311	0.117–0.824	0.019
LDL	0.918	0.691–1.220	0.554
Creatinine	1.010	1.005–1.016	<0.001	NS	NS	NS
WBC count	1.119	1.062–1.180	<0.001	NS	NS	NS
Neutrophil count	1.144	1.087–1.205	<0.001	1.115	1.044–1.190	0.001
Lymphocyte count	0.839	0.545–1.293	0.426
PLC > 198.00	1.220	0.702–2.119	0.481
NLR > 4.88	1.045	1.019–1.072	0.001	NS	NS	NS
PLC > 198.00 and NLR > 4.88	3.476	1.164–10.383	0.026	2.132	1.020–4.454	0.044

HR, hazard ratio; CI, confidence interval; NS, no statistical significance; CHD, coronary heart disease; LVEF, left ventricular ejection fraction; HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; WBC, white blood cell; PLC, platelet count; NLR, neutrophil-to-lymphocyte ratio.