Research Article
[Retracted] Clinical Value of Pleural Effusion and Serum MMP-3 and CYFRA21-1 Combined with ADA in Differential Diagnosis of Pleural Exudative Effusion
Table 2
Differential diagnostic value of pleural effusion and serum MMP-3, CYFRA21-1, and ADA in PEE.
| Index | AUC | 95% CI | Optimal cutoff value | Sensitivity (%) | Specificity (%) | Lower limit | Upper limit |
| Pleural effusion MMP-3 | 0.764 | 0.661 | 0.866 | 0.502 | 72.31 | 77.89 | Serum MMP-3 | 0.722 | 0.614 | 0.831 | 0.469 | 70.82 | 76.08 | Pleural effusion MMP-3 + serum MMP-3 | 0.810 | 0.716 | 0.904 | 0.607 | 73.91 | 86.79 | Pleural effusion CYFRA21-1 | 0.776 | 0.677 | 0.875 | 0.458 | 65.80 | 80.00 | Serum CYFRA21-1 | 0.748 | 0.645 | 0.852 | 0.464 | 74.19 | 72.21 | Pleural effusion CYFRA21-1 + serum CYFRA21-1 | 0.822 | 0.724 | 0.920 | 0.593 | 79.14 | 80.16 | Pleural effusion ADA | 0.762 | 0.646 | 0.858 | 0.556 | 75.20 | 80.40 | Serum ADA | 0.737 | 0.634 | 0.840 | 0.508 | 73.37 | 77.43 | Pleural effusion ADA + serum ADA | 0.836 | 0.747 | 0.924 | 0.636 | 81.58 | 82.02 |
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