The Association between Systemic Immune-Inflammation Index and All-Cause Mortality in Acute Ischemic Stroke Patients: Analysis from the MIMIC-IV Database
Table 2
Univariate Cox regression analysis.
Item
HR (95% CI)
Gender: male vs. female
0.92 (0.7, 1.21)
0.567
Age, years
1.02 (1.01, 1.03)
<0.001
Heart rate
1.01 (1.01, 1.02)
<0.001
MAP, mmHg
0.9968 (0.9897, 1.004)
0.383
Respiratory rate
1.05 (1.02, 1.07)
<0.001
Temperature (°C)
0.97 (0.82, 1.14)
0.679
SPO2
0.99 (0.95, 1.02)
0.357
Hypertension
1.13 (0.86, 1.49)
0.371
Hyperlipidemia
0.76 (0.58, 1)
0.051
Atrial fibrillation
1.13 (0.86, 1.49)
0.379
Myocardial infarct
1.2 (0.86, 1.67)
0.281
Congestive heart failure
0.95 (0.71, 1.29)
0.755
Charlson comorbidity
1.07 (1.02, 1.12)
0.006
Neutrophils (109/L)
1.08 (1.05, 1.11)
<0.001
Lymphocytes (109/L)
0.87 (0.74, 1.03)
0.1
Platelets (109/L)
1.0003 (0.9989, 1.0018)
0.638
WBC (109/L)
1.05 (1.03, 1.07)
<0.001
Hemoglobin (g/L)
0.9982 (0.9455, 1.0539)
0.949
RDW (109/L)
1.02 (0.95, 1.08)
0.624
BUN (mg/dL)
1.0043 (0.9988, 1.0099)
0.124
Anion gap (mmol/L)
1.05 (1.03, 1.08)
<0.001
Bicarbonate (mmol/L)
0.95 (0.92, 0.98)
0.002
Chloride (mmol/L)
0.9955 (0.9733, 1.0181)
0.692
Sodium (mmol/L)
1.0051 (0.9781, 1.0327)
0.716
Potassium (mmol/L)
0.93 (0.79, 1.09)
0.346
Glucose (mg/dL)
1.0018 (1.0008, 1.0028)
<0.001
INR
0.95 (0.78, 1.17)
0.659
PT seconds
0.9963 (0.9763, 1.0167)
0.719
PTT seconds
1.0036 (0.9964, 1.0108)
0.33
Warfarin
0.2 (0.12, 0.34)
<0.001
NOAC
0.1 (0.03, 0.3)
<0.001
Antiplatelet agents
0.46 (0.35, 0.61)
<0.001
PEGJ
0.1 (0.03, 0.31)
<0.001
Mechanical ventilation
2.49 (1.86, 3.33)
<0.001
APS III
1.02 (1.02, 1.02)
<0.001
SAPS II
1.04 (1.03, 1.05)
<0.001
OASIS
1.07 (1.05, 1.08)
<0.001
LODS (days)
1.16 (1.12, 1.2)
<0.001
SOFA
1.09 (1.06, 1.13)
<0.001
GCSMIN
0.89 (0.86, 0.92)
<0.001
LOS.ICU
0.94 (0.92, 0.97)
<0.001
LOS.hospital
0.81 (0.78, 0.84)
<0.001
HR, hazard ratio; CI, confidence interval; MAP, mean arterial pressure; SPO2, saturation of percutaneous oxygen; WBC, white blood cell; RDW, red blood cell distribution width; BUN, blood urea nitrogen; INR, international normalized ratio; PT, prothrombin time; PTT, partial thromboplastin time; NOAC, new oral anticoagulants; PEGJ, percutaneous gastrojejunostomy; APS III, acute physiology score III; SAPS II, simplified acute physiology score; OASIS, Oxford acute severity of illness score; LODS, logistic organ dysfunction score; SOFA, sequential organ failure assessment; GCS, Glasgow coma scale; LOS.ICU, length of stay in the ICU; LOS.hospital, length of stay in the hospital.