Research Article

The Association between Systemic Immune-Inflammation Index and All-Cause Mortality in Acute Ischemic Stroke Patients: Analysis from the MIMIC-IV Database

Table 2

Univariate Cox regression analysis.

ItemHR (95% CI)

Gender: male vs. female0.92 (0.7, 1.21)0.567
Age, years1.02 (1.01, 1.03)<0.001
Heart rate1.01 (1.01, 1.02)<0.001
MAP, mmHg0.9968 (0.9897, 1.004)0.383
Respiratory rate1.05 (1.02, 1.07)<0.001
Temperature (°C)0.97 (0.82, 1.14)0.679
SPO20.99 (0.95, 1.02)0.357
Hypertension1.13 (0.86, 1.49)0.371
Hyperlipidemia0.76 (0.58, 1)0.051
Atrial fibrillation1.13 (0.86, 1.49)0.379
Myocardial infarct1.2 (0.86, 1.67)0.281
Congestive heart failure0.95 (0.71, 1.29)0.755
Charlson comorbidity1.07 (1.02, 1.12)0.006
Neutrophils (109/L)1.08 (1.05, 1.11)<0.001
Lymphocytes (109/L)0.87 (0.74, 1.03)0.1
Platelets (109/L)1.0003 (0.9989, 1.0018)0.638
WBC (109/L)1.05 (1.03, 1.07)<0.001
Hemoglobin (g/L)0.9982 (0.9455, 1.0539)0.949
RDW (109/L)1.02 (0.95, 1.08)0.624
BUN (mg/dL)1.0043 (0.9988, 1.0099)0.124
Anion gap (mmol/L)1.05 (1.03, 1.08)<0.001
Bicarbonate (mmol/L)0.95 (0.92, 0.98)0.002
Chloride (mmol/L)0.9955 (0.9733, 1.0181)0.692
Sodium (mmol/L)1.0051 (0.9781, 1.0327)0.716
Potassium (mmol/L)0.93 (0.79, 1.09)0.346
Glucose (mg/dL)1.0018 (1.0008, 1.0028)<0.001
INR0.95 (0.78, 1.17)0.659
PT seconds0.9963 (0.9763, 1.0167)0.719
PTT seconds1.0036 (0.9964, 1.0108)0.33
Warfarin0.2 (0.12, 0.34)<0.001
NOAC0.1 (0.03, 0.3)<0.001
Antiplatelet agents0.46 (0.35, 0.61)<0.001
PEGJ0.1 (0.03, 0.31)<0.001
Mechanical ventilation2.49 (1.86, 3.33)<0.001
APS III1.02 (1.02, 1.02)<0.001
SAPS II1.04 (1.03, 1.05)<0.001
OASIS1.07 (1.05, 1.08)<0.001
LODS (days)1.16 (1.12, 1.2)<0.001
SOFA1.09 (1.06, 1.13)<0.001
GCSMIN0.89 (0.86, 0.92)<0.001
LOS.ICU0.94 (0.92, 0.97)<0.001
LOS.hospital0.81 (0.78, 0.84)<0.001

HR, hazard ratio; CI, confidence interval; MAP, mean arterial pressure; SPO2, saturation of percutaneous oxygen; WBC, white blood cell; RDW, red blood cell distribution width; BUN, blood urea nitrogen; INR, international normalized ratio; PT, prothrombin time; PTT, partial thromboplastin time; NOAC, new oral anticoagulants; PEGJ, percutaneous gastrojejunostomy; APS III, acute physiology score III; SAPS II, simplified acute physiology score; OASIS, Oxford acute severity of illness score; LODS, logistic organ dysfunction score; SOFA, sequential organ failure assessment; GCS, Glasgow coma scale; LOS.ICU, length of stay in the ICU; LOS.hospital, length of stay in the hospital.