Review Article

[Retracted] Preparation of PCL Electrospun Fibers Loaded with Cisplatin and Their Potential Application for the Treatment of Prostate Cancer

Table 1

Advantages and disadvantages of nanofibers as drug-carrying agents [43, 44].

AdvantagesDisadvantages

High surface-to-volume ratio accelerates drug solubility in the aqueous environment and improves drug efficiency.Scaffolds of nanofibers might be used as templates for the formation of conductive drug-loaded polymer systems.
Surface structure and morphologies of nanofibers make it possible to curb the drug dose and the rate at which the drug is released.Production of nanofibers requires the use of organic solvents and it is impossible to control the 3-dimensional pore structure.
Bioactivity of the drug is maintained because biodegradable polymers shield the drug from corrosive attack by enzymes and gastric acid.