Research Article
Relationship of Serum IL-12 to Inflammation, Hematoma Volume, and Prognosis in Patients With Intracerebral Hemorrhage
Table 3
Factors associated with early neurological deterioration in patients with ICH.
| | Variables | Early neurological deterioration | value | | Yes (n = 66) | No (n = 143) |
| | Gender (male/female) | 40/26 | 81/62 | 0.590 | | Age (years) | 70.2 ± 15.4 | 65.1 ± 21.3 | 0.0035 | | Admission time (hours) | 6.2 (9.5) | 5.6 (8.9) | 0.426 | | Blood collection time (hours) | 7.2 (7.1) | 6.8 (7.3) | 0.194 | | Initial SBP (mmHg) | 162.3 ± 23.5 | 159.4 ± 26.8 | 0.438 | | Initial DBP (mmHg) | 93.8 ± 19.6 | 90.4 ± 23.2 | 0.208 | | Hypertension (n (%)) | 47 (71.2) | 88 (61.5) | 0.174 | | Current smoking (n (%)) | 22 (33.3) | 45 (31.5) | 0.788 | | Atrial fibrillation (n (%)) | 18 (27.3) | 28 (19.6) | 0.212 | | Lobar hemorrhage (n (%)) | 18 (27.3) | 27 (18.9) | 0.170 | | Infratentorial hemorrhage (n (%)) | 12 (18.2) | 25 (17.5) | 0.902 | | Intraventricular hemorrhage (n (%)) | 17 (25.8) | 32 (22.4) | 0.592 | | Admission NIHSS | 16.0 (9.0) | 8.0 (8.0) | <0.001 | | Hematoma volume (mL) | 21.6 (12.3) | 16.5 (14.3) | 0.005 | | WBC (×109/L) | 10.8 ± 2.5 | 9.0 ± 2.6 | 0.032 | | Serum glucose (mmol/L) | 8.2 ± 1.5 | 7.0 ± 1.1 | 0.019 | | Serum CRP (mg/L) | 26.7 (5.68) | 19.7 (9.8) | <0.001 | | Serum TNF-α (pg/mL) | 70.0 (14.8) | 56.2 (21.4) | <0.001 | | Serum IL-12 (pg/mL) | 82.9 (14.9) | 65.8 (26.3) | <0.001 |
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