Research Article

Relationship of Serum IL-12 to Inflammation, Hematoma Volume, and Prognosis in Patients With Intracerebral Hemorrhage

Table 4

Factors associated with 3-month poor outcome in patients with ICH.

VariablesEarly neurological deterioration value
mRS (3–6) (n = 82)mRS (0–2) (n = 127)

Gender (male/female)50/3271/560.469
Age (years)69.3 ± 16.866.1 ± 15.4<0.001
Admission time (hours)6.0 (8.3)5.8 (7.2)0.389
Blood collection time (hours)7.0 (7.3)6.9 (7.2)0.441
Initial SBP (mmHg)163.5 ± 24.2160.8 ± 26.80.512
Initial DBP (mmHg)92.7 ± 19.292.2 ± 21.30.869
Hypertension (n (%))57 (69.5)78 (61.4)0.232
Current smoking (n (%))29 (35.4)38 (29.9)0.376
Atrial fibrillation (n (%))21 (25.6)25 (19.7)0.313
Lobar hemorrhage (n (%))20 (24.4)25 (19.7)0.419
Infratentorial hemorrhage (n (%))16 (19.5)21 (16.5)0.582
Intraventricular hemorrhage (n (%))21 (25.6)28 (22.0)0.553
Admission NIHSS15.5 (9.0)7.0 (8.0)<0.001
Hematoma volume (mL)19.9 (12.0)15.8 (14.5)0.005
WBC (×109/L)10.2 ± 2.89.4 ± 1.80.038
Serum glucose (mmol/L)8.0 ± 1.77.1 ± 1.20.041
Serum CRP (mg/L)25.6 (6.9)19.3 (9.8)<0.001
Serum TNF-α (pg/mL)69.0 (20.0)56.2 (22.0)<0.001
Serum IL-12 (pg/mL)79.0 (17.0)65.3 (28.6)<0.001