Research Article

Evaluation of the Potential for Improvement of Clinical Outcomes in Trauma Patients with Massive Hemorrhage by Maintaining a High Plasma-to-Red Blood Cell Ratio during the First Hour of Hospitalization

Table 1

General characteristics of each group (N = 1,059).

NPMT (n = 1008)MTP (n = 51)

Age (years, mean)51450.017
Male773 (76.7%)35 (68.6%)0.187
Glasgow coma scale score (mean)9.29.70.477
Systolic blood pressure
 Mean (mmHg)10174<0.001
n with ≤90 mmHg377 (37.4%)30 (58.8%)0.002
Diastolic blood pressure
 Mean (mmHg)64490.005
Heart rate (n)91947
 Mean (beats/min)1021080.115
n with ≥120 beats/min241 (26.2%)12 (25.5%)0.916
Assessment of blood consumption score (n)68043
n with ≥2150 (22.1%)13 (30.2%)0.214
Focused assessment with sonography in trauma (n)73445
 Positive194 (26.6%)12 (26.7%)0.972
Mechanism of injury
 Blunt injury924470.902
 Penetrating injury844
Hemoglobin level (n)96750
 Mean (g/dL)10.811.60.006
n with ≤11 g/dL494 (51.1%)18 (36.0%)0.037
International normalized ratio (n)92947
 Mean1.41.60.088
n with ratio >1.5210 (22.6%)14 (29.8%)0.253
Lactic acid (n)97651
 Mean (mmol/L)6.06.90.128
n with ≥2.0 mmol/L910 (93.2%)50 (98.0%)0.176
Base excess (n)96251
 Mean (mmol/L)−9.0−9.90.279
n with score ≤ −4 mmol/L793 (82.4%)46 (90.2%)0.152
Injury severity score (n)96951
 Mean28.937.10.002
AIS head (n)46225
 Mean3.93.50.177
AIS face (n)23911
 Mean1.82.00.401
AIS chest (n)23911
 Mean3.23.40.178
AIS abdomen (n)66340
 Mean3.23.10.594
AIS extremity (n)67739
 Mean3.03.70.002
AIS external (n)24824
 Mean1.11.10.546

AIS: abbreviated injury scale; NPMT: nonprotocolised massive transfusion; MTP: massive transfusion protocol. P values less than 0.05 were indicated in bold.