Review Article

Minimally Invasive Endovascular Repair for Nondissected Ascending Aortic Disease: A Systematic Review

Table 5

Endovascular treatment of ascending aortic disease: death cases.

YearsGenderAgeAA diseaseBasic diseaseSurgical historyComplicationPostoperative medicationPostoperative survival time and cause of deathAutopsy

2023F52AAPsAscending aorta and a bicuspid aortic valve with moderate mixed aortic valve diseaseBentall’s procedure using a 27-mm biointegral valve aortic bioconduit and mitral valve annuloplastyWound bleeding, hemoptysis, dizziness and empyemaRed blood cell transfusions and iron infusions/long-term antibiotics7 m/the patient subsequently made the decision not to proceed with any further surgery and declined antibiotic therapy and died 7 months after the first endovascular stent graft procedureNo autopsy was conducted

2021F57PAUsChronic rheumatic heart disease/ascending aortic pseudoaneurysm fistulaMitral valve replacement surgery, open surgery using patches due to ascending aortic pseudoaneurysmNoneAspirin
Warfarin
6 m/the patient remained asymptomatic after discharge until 6 months when she died of a possible cardiogenic stroke after discontinuing anticoagulantsNo autopsy was conducted

2018M56AA ruptureMarfan syndrome/acute respiratory failureSurgical history of open total arch replacement and “whole block” island reimplantation of supraaortic vessels, descending TEVAR, two remedian sternotomy to repair false aneurysms, and chest anterior transposition flapMultiple drug resistance pneumoniaNR32 d/died of multiple drug resistance pneumonia 32 days after operationNo autopsy was conducted

2018F74AAPsNoneNoneNoneMetoprolol
Furosemide
Lisinopril
3 m/4.0 cm long longitudinal tear at the minor curvature of the aorta leading to pericardial hemorrhageThe autopsy confirmed that the cause of death was pericardial hematocele, which was a longitudinal tear 4.0 centimeters long at the small curvature of the ascending aorta without any associated dissection

2014MNRAAPsNoneNRNRNR14 d/sudden respiratory distress and ventricular fibrillationNo autopsy was conducted

2013M67AAPsNoneAscending aorta replacement, thoracic descending aorta covered stent implantationLeft hemisphere stroke, splenic infarctionClopidogrel
Aspirin
6 m/sudden death before follow-up CT; no autopsy was conductedNo autopsy was conducted

2011M74AAPsMyocardial infarct/severe COPD/severe addiction to smokingNoneRupture of left ventricular wallNR1 d/multiple organ failure within 24 hoursNo autopsy was conducted

2007F82AAPsChronic congestive heart failureEmergency repair of acute ascending aortic dissectionMultiple organ failureNR15 d/on the 15th day after surgery, the patient developed an acute brainstem stroke and diedAutopsy confirmed that the covered stent was not displaced, and the coronary artery orifice and brachiocephalic artery were unobstructed

Values are expressed as numbers and % or the mean ± SD. AAPs: ascending aorta pseudoaneurysms; PAUs: penetrating aortic ulcers; NR: no report; AA: ascending aorta.