Relationship between Nonhepatic Serum Ammonia Levels and Sepsis-Associated Encephalopathy: A Retrospective Cohort Study

Table 2

Multivariate logistic analysis of risk factors in patients with SAE.

		OR	95.0% CI
			Lower	Upper
Age	0.154	0.990	0.997	1.004
Coexisting illness (n (%))
Hypertension	0.044	0.581	0.343	0.985
Renal	0.241	0.780	0.514	1.182
Site of infection (n (%))
Urinary	0.357	1.429	0.668	3.056
Lung	0.316	0.645	0.274	1.520
Catheter	0.411	0.609	0.187	1.987
Abdominal cavity	0.609	0.796	0.331	1.911
Microbiology type (n (%))
Klebsiella	0.076	0.635	0.385	1.048
Escherichia coli	0.014	0.587	0.384	0.897
Pseudomonas aeruginosa	0.108	0.625	0.352	1.109
Staphylococcus aureus	0.02	0.290	0.102	0.824
Laboratory parameters
Platelet (×10^9/L)	0.967	1.000	0.998	1.002
Serum ammonia level ≥45 (μmol/L)	<0.001	3.508	2.336	5.269
Analgesic and sedative drugs (n (%))
Propofol	0.022	0.348	0.141	0.859
Opioids	0.009	3.433	1.360	8.669
Mechanical ventilation (n (%))	0.129	1.320	0.922	1.889
Score system
SOFA	<0.001	1.126	1.062	1.194

SOFA: Sequential Organ Failure Assessment.