Research Article

Association between Red Blood Cell Distribution Width and Short-Term Mortality in Patients with Paralytic Intestinal Obstruction: Retrospective Data Analysis Based on the MIMIC-III Database

Table 2

Univariate analysis for 28-day mortality in critically ill patients with paralytic intestinal obstruction.

CharacteristicStatisticsOR (95%CI) value

RDW start15.4 (2.1)1.25 (1.15, 1.36)<0.001
Age (years)62.8 (16.1)1.02 (1.01, 1.03)0.001
Sex, n (%)
 Male497 (64.3)Reference
 Female276 (35.7)0.99 (0.66, 1.47)0.944
Admission type, n (%)
 Emergency576 (74.5)Reference
 Elective197 (25.5)0.72 (0.45, 1.14)0.158
Ethnicity, n (%)
 White565 (73.1)Reference
 Asian22 (2.8)0.78 (0.23, 2.69)0.696
 Black71 (9.2)0.81 (0.40, 1.64)0.56
 Others115 (14.9)0.98 (0.57, 1.68)0.939
DBP (mmHg)61.3 (10.4)0.99 (0.97, 1.01)0.212
SBP (mmHg)118.0 (17.0)0.98 (0.97, 1.00)0.014
Laboratory parameters
 Hematocrit (%)31.4 (5.2)0.95 (0.91, 0.99)0.015
 Serum potassium (mEq/L)4.2 (0.6)0.91 (0.65, 1.26)0.553
 BUN (mg/dL)20.5 (14.0–34.0)1.00 (0.99, 1.01)0.548
 White blood cell count (K/uL)11.0 (8.1–16.0)1.00 (0.98, 1.02)0.899
 Platelet count (K/uL)202.0 (137.0–275.0)1.00 (1.00, 1.00)0.077
 Hemoglobin (g/dL)10.6 (1.8)0.83 (0.74, 0.94)0.002
 Serum glucose (mg/dL)139.8 (53.7)0.99 (0.99, 1.00)0.009
 Serum creatinine (mg/dL)1.0 (0.8–1.6)0.99 (0.87, 1.14)0.902
 Serum anion gap (mEq/L)13.9 (3.7)1.01 (0.96, 1.07)0.577
Scoring systems
 APS III50.8 (22.3)1.01 (1.00, 1.02)0.059
 OASIS33.5 (9.1)1.04 (1.02, 1.06)<0.001
 qSOFA1.8 (0.7)1.20 (0.91, 1.58)0.191
 MLODS3.0 (1.0–5.0)1.07 (1.00, 1.14)0.068
Comorbidities
Congestive heart failure, n (%)
 No615 (79.6)Reference
 Yes158 (20.4)1.96 (1.28, 3.01)0.002
Hypertension, n (%)
 No678 (87.7)Reference
 Yes95 (12.3)0.86 (0.47, 1.58)0.635
Renal failure, n (%)
 No659 (85.3)Reference
 Yes114 (14.7)1.10 (0.65, 1.86)0.728
Liver disease, n (%)
 No687 (88.9)Reference
 Yes86 (11.1)2.05 (1.22, 3.45)0.007
Coagulopathy, n (%)
 No605 (78.3)Reference
 Yes168 (21.7)1.95 (1.28, 2.96)0.002
Chronic pulmonary disease, n (%)
 No602 (77.9)Reference
 Yes171 (22.1)1.57 (1.02, 2.41)0.038
Pulmonary circulation, n (%)
 NoReference
 Yes54 (7.0)1.17 (0.57, 2.39)0.668
Time in ICU (days)3.9 (2.0–8.7)1.03 (1.01, 1.04)0.76
Time in hospital (days)15.1 (9.8–25.0)1.02 (1.01, 1.03)<0.001

Notes: normally distributed data are presented as the mean (SD) (analysis of variance); non-normally distributed data are presented as median (IQR) (nonparametric Wilcoxon test); categorical variables are presented as n (%) (Chi-square test). Abbreviations: RDW, red cell distribution width; BUN, blood urea nitrogen; SBP, systolic blood pressure; DBP, diastolic blood pressure; APS III, acute Physiology Score III; OASIS, Oxford acute severity of illness score; qSOFA, quick sequential organ failure assessment score; MLODS, modified logistic organ dysfunction system; ICU, intensive care unit; SD, standard deviation; IQR, interquartile ranges.