Research Progress on the Mechanism and Management of Septic Cardiomyopathy: A Comprehensive Review

Figure 1

Pathophysiology of septic cardiomyopathy. This illustration shows the potential mechanisms contributed to septic cardiomyopathy. The pathways involved are the activation of inflammatory response including PAMPs, DAMPs, cytokines, NO, NOS, and complements; disorders of exosomes, miRNAs and lncRNAs; mitochondrial dysfunction; and the imbalance of calcium handling. PAMPs, pathogen-associated molecular patterns; DAMPs, damage-associated molecular patterns; NO, nitric oxide; NOS, nitric oxide synthase; LncRNA, long noncoding RNA.