Review Article

Research Progress on the Mechanism and Management of Septic Cardiomyopathy: A Comprehensive Review

Table 1

Recent studies of septic cardiomyopathy.

ReferencesPopulationsTime of echocardiographyResults

Bouhemad et al. [9]45On days 1, 2, 3, 4, 7, and 1018% with a reversible increase in cTnI and LVEF < 50%, 18% with a reversible increase in cTnI, and impairment of LV relaxation
Furian et al. [10]45Within the first 24 h, again 72 h, and 7 days after admission33% with LVEF < 55%, and 30% with RV tissue Doppler peak systolic velocity <12 cm/s
Hanumanth et al. [11]359Within 72 h of admission, 6 months prior to admission or within 3 months after the diagnosis of sepsis5.3% with a new onset decline in LVEF ≤ 50%, or ≥ 10% decline in LVEF compared to baseline in patients with reduced EF
Landesberg et al. [12]262On the day after admission to ICU, and the next day23.3% with LVEF ≤ 50%, and 50% with diastolic dysfunction
Liang et al. [13]353028.2% with LVEF < 50%, or with global LV hypokinesis or LV systolic dysfunction
Lu et al. [14]100Within 24 h of admission to ICU21% with LV systolic dysfunction, 40% with LV diastolic dysfunction, and 12% with RV systolic dysfunction
Orde et al. [15]60Within 24 h of meeting sepsis criteria32% with RV dysfunction, 20% with LV dysfunction, and 17% with both LV and RV dysfunction
Pulido et al. [16]106Within 24 h, at day 5 or day of dismissal of ICU37% with LV diastolic dysfunction, 27% with LV systolic dysfunction, and 31% with RV dysfunction
Song et al. [17]342Within 48 h after ICU admission14.3% with LVEF < 50% or ≥ 10% decrease in baseline EF that recovered within 2 weeks
Sato et al. [18]210Within 24 h of admission13.8% with LVEF < 50% or a ≥ 10% decrease compared to the baseline EF which recovered within 2 weeks
Song et al. [19]143Within 24 h after admission to ICU18.2% with LVEF < 50%

LV, left ventricular; LVEF, LV ejection fraction; RV, right ventricular; cTnI, cardiac troponin I; ICU, intensive care unit.