Research Article

The Predictive Role of Lactate in the Emergency Department in Patients with Severe Dyspnea

Table 1

Baseline patients’ characteristics.

DeathSurvival value
n = 38n = 70

Gender (women/men)20/18 (52.6%/47.4%)33/37 (47.1%/52.9%)0.5834

Median age, years, median (Q1–Q3)79.5 (69–87)71 (53–80)0.0043

Reason of admission, n (%)Dyspnea 7 (18%)Dyspnea 36 (51%)0.0009
Heart failure 14 (37%)Heart failure 7 (10%)0.0017
Pneumonia 9 (24%)Pneumonia 7 (10%)0.0865
ND 8 (21%)ND 20 (29%)0.4927

Triage level, n (%)Red 13 (34%)Red 5 (7%)0.0007
Orange 9 (24%)Orange 12 (17%)0.4511
Yellow 15 (39%)Yellow 49 (70%)0.6548
Green 1 (3%)Green 4 (6%)0.0038

Comorbidities, n (%)Post-SCA 8 (21%)Post-SCA 2 (3%)0.0034
DM2 17 (45%)DM2 13 (19%)0.0064
Asthma 6 (16%)Asthma 2 (3%)0.0216
NPL 6 (16%)NPL 2 (3%)0.0216
CKD 13 (34%)CKD 10 (14%)0.0254
SCA at ED 7 (18%)SCA at ED 3 (4%)0.0314
HF 20 (53%)HF 23 (33%),0.0636
COVID-19 5 (13%)COVID-19 2 (3%)0.0938
OHS 1 (3%)OHS 0 (0%)0.3519
ILDs 1 (3%)ILDs 6 (9%)0.4175
COPD 3 (8%)COPD 9 (13%)0.5343
HT 22 (58%)HT 41 (59%),>0.9999
Post-ACS 6 (16%)Post-ACS 10 (14%)>0.9999
Stroke 2 (5%)Stroke 5 (7%)>0.9999
Post-COVID-19 1 (3%)Post-COVID-19 1 (1%)>0.9999
OSA 1 (3%)OSA 2 (3%)>0.9999
PE 1 (3%)PE 1 (1%)>0.9999

SBP median (Q1–Q3), mmHg109 (85–130)140 (123–167)<0.0001

DBP median (Q1–Q3), mmHg66 (46–78)84 (70–95)<0.0001

MAP median (Q1–Q3), mmHg83 (58–93)103 (89–118)<0.0001

SpO2 median (Q1–Q3), %92 (82–96)96 (92–98)0.0037

Oxygen therapy at the ED, n (%)No data 3 (8%)No data 5 (7%)
Own breath 9 (24%)Own breath 36 (51%)0.006
Oxygen mask 15 (39%)Oxygen mask 23 (33%)0.5202
HFNOT 2 (5%)HFNOT 0 (0%)0.1202
IMV 8 (21%)IMV 5 (7%)0.0575
NIV 1 (3%)NIV 1 (1%)>0.9999

Time spent at the ED, median (Q1–Q3), hours6.75 (4–12)5 (3.5–8.5)0.21

ACS, acute coronary syndrome; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; DM2, diabetes mellitus type 2; DBP, diastolic blood pressure; ED, emergency department; HF, heart failure; HFNOT, high-flow nasal oxygen therapy; HT, hypertension; ILDs, interstitial lung diseases; IMV, invasive mechanical ventilation; IQR, interquartile range; NIV, noninvasive ventilation; NPL, neoplasma; ND, neurological disorders; NS, nonsignificant; OHS, obesity hypoventilation syndrome; OSA, obstructive sleep apnea; PE, pulmonary embolism; SCA, sudden cardiac arrest; SBP, systolic blood pressure. Continuous data were presented as median and IQR. Categorical data were presented as total number and %. For the clarity, in each table the P < 0.05 has been highlighted in bold letters.