Research Article

Changes in Liver and Splenic Stiffness after Direct-Acting Antiviral Therapy in Chronic Hepatitis C: A Single-Centre, Prospective, Observational Study

Table 2

Receiver operating characteristics (ROC) associated with remaining portal hypertension in patients with a spleen stiffness value of ≥3.4 m/s at pretreatment (high SSM group, n =48).

CharacteristicsCOVAUCSensitivitySpecificity

Age, years740.54350.520.65
LSM, m/s1.930.68960.480.91
ALB, g/dL3.80.56700.560.61
ALT, IU/L350.66260.640.70
PLT, ×104/μL12.60.61650.600.83

Abbreviations: SSM, spleen stiffness measurement; LSM, liver stiffness measurement; ALB, albumin; ALT, alanine aminotransferase; PLT, platelet count; COV, cut-off value; AUC, area under the receiver operating characteristic curve.