Changes in Liver and Splenic Stiffness after Direct-Acting Antiviral Therapy in Chronic Hepatitis C: A Single-Centre, Prospective, Observational Study

Table 2

Receiver operating characteristics (ROC) associated with remaining portal hypertension in patients with a spleen stiffness value of ≥3.4 m/s at pretreatment (high SSM group, n =48).

Characteristics	COV	AUC	Sensitivity	Specificity
Age, years	74	0.5435	0.52	0.65
LSM, m/s	1.93	0.6896	0.48	0.91
ALB, g/dL	3.8	0.5670	0.56	0.61
ALT, IU/L	35	0.6626	0.64	0.70
PLT, ×10^4/μL	12.6	0.6165	0.60	0.83

Abbreviations: SSM, spleen stiffness measurement; LSM, liver stiffness measurement; ALB, albumin; ALT, alanine aminotransferase; PLT, platelet count; COV, cut-off value; AUC, area under the receiver operating characteristic curve.