Lafutidine 10 mg versus Rabeprazole 20 mg in the Treatment of Patients with Heartburn-Dominant Uninvestigated Dyspepsia: A Randomized, Multicentric Trial
Table 3
Symptom score (Mean ± SD) at baseline and after 2 and 4 weeks.
Lafutidine
Rabeprazole
value for difference between treatments
Mean score ± S.D. ()
Mean score ± S.D. ()
Epigastric pain
Baseline
4.86 ± 1.19
4.87 ± 1.42
NS
Week 2
2.86 ± 0.71*
3.17 ± 0.96*
.002
Week 4
1.28 ± 0.74*
1.91 ± 1.07*
<.0001
Heartburn
Baseline
5.07 ± 0.99
5.13 ± 0.91
NS
Week 2
2.71 ± 0.70*
2.98 ± 0.94*
.0224
Week 4
1.28 ± 0.71*
2.04 ± 1.03*
<.0001
Abdominal bloating
Baseline
4.92 ± 1.08
4.97 ± 1.25
NS
Week 2
2.60 ± 0.74*
2.97 ± 1.06*
.0075
Week 4
1.36 ± 0.83*
1.95 ± 1.00*
<.0001
*
Value less than .001 versus baseline, within the group. NS: not significant ().
