Clinical Characteristics and Surgical Prognosis of Hepatocellular Carcinoma with Bile Duct Invasion

Table 2

Pathological and surgical parameters of HCC patients with and without bile duct invasion.

Tumor status parameters	Bile duct invasion				𝑃 value
	Yes (𝑛=35)		No (𝑛=378)
	Number or mean	% or SE	Number or mean	% or SE
Tumor number
Single/multiple	20/15	57.1/42.9	297/81	78.6/21.4	0.006
Maximal tumor size
≤5 cm/>5 cm	11/24	31.4/68.6	216/162	57.1/42.9	0.004
Capsule formation
Present/absent	11/24	31.4/68.6	116/262	30.7/69.3	1.000
Portal vein invasion
Positive/negative	10/25	28.6/71.4	38/340	10.1/89.9	0.003
Cellular differentiation
Well/moderately/poorly	3/22/10	8.6/62.9/28.5	25/252/101	6.1/64.2/29.7	0.864
Surgical mode
Nonanatomic/anatomic	26/9	74.3/26.7	239/139	63.2/36.8	0.215
Surgical margin
<1 cm/≥1 cm	23/12	65.7/34.3	175/203	46.3/53.7	0.034
Intraoperative blood transfusion (mL)	602.9	87.4	658.7	23.4	0.493
Operation time (h)	5.6	1.2	4.2	0.5	0.128
Postoperative morbidity
Presence/absence	9/26	25.7/74.3	135/243	35.7/64.3	0.235
Hospital stay (d)	24.6	1.6	23.6	0.8	0.683

HCC: hepatocellular carcinoma; SE: standard error.
The bold value means “𝑃<0.05” or “statistically different”.