Narrow-Band Imaging Magnifying Endoscopy versus Lugol Chromoendoscopy with Pink-Color Sign Assessment in the Diagnosis of Superficial Esophageal Squamous Neoplasms: A Randomised Noninferiority Trial

Table 4

Comparison of diagnostic outcomes between NBI-ME and LCE-PS.

	NBI-ME	LCE-PS
Sensitivity, % (95% CI)	82.2 (67.9–92.0)	80.5 (65.1–91.2)	NS
Specificity, % (95% CI)	95.1 (88.9–98.4)	94.3 (88.1–97.9)	NS
PPV, % (95% CI)	88.1 (74.4–96.0)	84.6 (69.5–94.1)	NS
NPV, % (95% CI)	92.4 (85.5–96.7)	92.6 (85.9–96.7)	NS
Overall accuracy, % (95% CI)	91.2 (85.4–95.2)	90.5 (84.5–94.7)	NS

NBI-ME, narrow-band imaging magnifying endoscopy; LCE-PS, Lugol chromoendoscopy with pink-color sign assessment; LGIN, low-grade intraepithelial neoplasia; SESCC, superficial esophageal squamous cell carcinoma; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; NS, not significant; Pearson’s test.