Nephroprotective Potential of Human Albumin Infusion: A Narrative Review

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Effect</td><td align="left">Mechanisms</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">Antioxidation</td><td align="left">Increase of plasma thiols</td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">Anti-inflammation</td><td align="left">(i) Modulation of cytokine actions<br/>(ii) Protection of glycocalyx</td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">Modulation of nitric oxide</td><td align="left">—</td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">Ligation of endotoxin </td><td align="left">—</td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">Pharmacokinetic and pharmacodynamic effects</td><td align="left">(i) Transport of drugs <br/>(ii) Modulation of drug effects </td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Effects of human albumin infusion unrelated to oncotic pressure [<a href="/journals/grp/2015/912839/#B6">6</a>, <a href="/journals/grp/2015/912839/#B18">17</a>, <a href="/journals/grp/2015/912839/#B20">19</a>–<a href="/journals/grp/2015/912839/#B23">22</a>].

Gastroenterology Research and Practice

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Table 1

Table 1: Nephroprotective Potential of Human Albumin Infusion: A Narrative Review 