Serum Immunoglobulin A (IgA) Level Is a Potential Biomarker Indicating Cirrhosis during Chronic Hepatitis B Infection

Table 3

Uni- and multivariate analysis of factors associated with hepatic cirrhosis.

	Univariable			Multivariable
	OR	95% CI		OR	95% CI
Age (y)	1.057	1.025–1.090	0.001	1.021	0.978–1.065	0.346
Total protein (g/L)	0.982	0.936–1.031	0.459	—	—	—
Albumin (g/L)	0.854	0.793–0.918	0.001	0.849	0.732–0.984	0.030
Platelets (×10^9/L)	0.982	0.975–0.989	0.001	0.981	0.972–0.990	0.001
INR	1.206	0.429–3.548	0.727	—	—	—
IgM (mg/dL)	1.002	0.998–1.006	0.361	—	—	—
IgA (mg/dL)	1.005	1.003–1.008	0.001	1.006	1.002–1.009	0.002
IgG (mg/dL)	1.001	1.000–1.001	0.043	0.999	0.998–1.001	0.333

INR, international normalized ratio; Ig, immunoglobulin.