Epithelial-Mesenchymal Transition Phenotype, Metformin, and Survival for Colorectal Cancer Patients with Diabetes Mellitus II

Table 2

Associations between expression of E-cadherin, vimentin, and clinicopathologic characteristics.

Variable	Category	E-cadherin			Vimentin
		Positive	Negative		Positive	Negative
Age		64.24, mean	63.19, mean	0.639	64.62, mean	62.69, mean	0.501
Gender	Female	15	20	0.449	18	17	0.715
	Male	34	33		37	30
Drinking history	Yes	9	11	0.762	7	13	0.058
	No	40	42		48	34
Smoking history	Yes	16	14	0.490	16	14	0.939
	No	33	39		39	33
Family history	Yes	4	3	0.708	3	4	0.543
	No	45	50		52	43
BMI		25.04, mean	24.83, mean	0.876	24.68, mean	25.2, mean	0.888
CEA		8.24, mean	14.23, mean	0.007	13.76, mean	8.75, mean	0.105
CA19-9		23.46, mean	36.58, mean	0.048	42.27, mean	17.31, mean	0.009
Sulfonylurea	Yes	27	20	0.079	24	23	0.592
	No	22	33		31	24
Insulin	Yes	13	21	0.161	24	11	0.032
	No	36	32		31	36
Site	Right	9	10	0.934	9	10	0.770
	Transverse	2	3		2	3
	Left	2	4		4	2
	Sigmoid	10	9		9	10
	Rectum	26	27		31	22
Histologic grade	I-II	40	45	0.658	43	42	0.131
	III	9	8		12	5
T	T1–3	35	17	<0.001	23	29	0.045
	T4	14	36		32	18
N	N0	35	25	0.013	24	36	0.001
	N1-2	14	28		31	11

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