Modulation of Colorectal Cancer Risk by Polymorphisms in 51Gln/His, 64Ile/Val, and 148Asp/Glu of APEX Gene; 23Gly/Ala of XPA Gene; and 689Ser/Arg of ERCC4 Gene

Table 2

The distribution of genotypes and allele frequencies and the analysis of the odds ratio (OR) for 51Gln/His polymorphism of APEX gene in patients with colorectal cancer (CRC) and the control group.

Genotype/allele	Patients ()	Controls ()	OR (95% CI)
Gln/Gln	69	92	1 (ref)	—
Gln/His	206	161	1.706 (1.174–2.480)	0.005
His/His	36	49	0.979 (0.576–1.667)	0.920
Gln	344	345	1 (ref)	—
His	278	259	1.077 (0.859–1.349)	0.522

Genotype distribution in the Hardy-Weinberg equilibrium, χ² = 0.125.
Values set in italics denote statistical significance.