Thickness of Subcutaneous Fat Is a Predictive Factor of Incisional Surgical Site Infection in Crohn’s Disease Surgery: A Retrospective Study
Table 1
Clinical and operational characteristics of patients in the research group.
Variable
Incisional SSI
value
Present ()
Absent ()
Gender (male/female)
41/20
126/59
0.507
Age (years)
36.5 ± 13.3
35.5 ± 12.7
0.593
Duration of disease (months)
65.6 ± 60.5
70.9 ± 61.1
0.554
Thickness of subcutaneous fat (mm)
13.7 ± 7.7
9.9 ± 6.1
<0.001
Disease behavior, (%)
0.203
Stricture
38 (62.3)
87 (47.0)
—
Penetration
21 (34.4)
91 (49.2)
—
Others
2 (3.3)
7 (3.8)
—
Disease location, (%)
0.373
Ileum
17 (27.9)
65 (35.1)
—
Colon
6 (9.8)
25 (13.5)
—
Ileocolon
38 (62.3)
93 (50.3)
—
Upper digestive tract
0 (0)
2 (1.1)
—
Perianal disease, (%)
15 (24.6)
61 (33.0)
0.219
Abdominal abscess, (%)
10 (16.4)
15 (8.1)
0.063
Previous abdominal surgery for CD, (%)
0.119
0
25 (41.0)
102 (55.1)
—
1
26 (42.7)
65 (35.2)
—
>1
10 (16.3)
18 (9.7)
—
Smoking, (%)
10 (16.3)
15 (8.1)
0.063
Length of preoperative hospitalization (days)
9.7 ± 16.5
8.1 ± 4.6
0.222
BMI (kg/m2)
17.4 ± 5.5
16.7 ± 5.0
0.380
Preoperative PN, (%)
13 (21.3)
34 (18.4)
0.613
Preoperative EN, (%)
47 (77.0)
157 (84.9)
0.159
Preoperative drug administration, (%)
5-ASA
15 (24.6)
59 (31.9)
0.281
Steroids
5 (8.2)
12 (6.5)
0.771
Immunosuppressant
20 (32.8)
60 (32.4)
0.959
Anti-TNF α antibody
6 (9.8)
12 (6.5)
0.400
Emergency operation, (%)
5 (8.2)
11 (5.9)
0.553
Surgical approach, (%)
0.117
Laparotomy
52 (85.2)
140 (75.7)
—
Laparoscopic
9 (14.8)
45 (24.3)
—
Anastomosis position, (%)
0.255
Nonanastomosis
11 (18.0)
39 (21.1)
—
Ileal anastomosis
15 (24.6)
62 (33.5)
—
Ileocolostomy
35 (57.4)
84 (45.4)
—
Stoma creation, (%)
0.532
Ileostomy
13 (21.3)
44 (23.8)
—
Colostomy
4 (6.6)
3 (1.7)
—
Length of incision (cm)
12.2 ± 3.5
10.6 ± 4.2
0.009
Incision class, (%)
0.011
Contaminated
51 (83.6)
174 (94.1)
—
Dirty
10 (16.4)
11 (5.9)
—
Duration of operation (min)
148.6 ± 49.5
141.2 ± 52.5
0.337
Intraoperative blood loss (mL)
218.2 ± 157.4
182.5 ± 116.2
0.059
Postoperative transferred to ICU, (%)
10 (16.4)
19 (10.3)
0.189
Postoperative IASCs, (%)
0.020
Anastomotic leak
3 (8.2)
2 (1.1)
—
Intra-abdominal abscess
3 (4.9)
1 (0.5)
—
Enterocutaneous fistula
1 (1.6)
1 (0.5)
—
Reoperation, (%)
2 (3.3)
1 (0.5)
0.153
Data are reported as the number of patients (%) or mean ± SD. SSI: surgical site infection; CD: Crohn’s disease; BMI: body mass index; PN: parenteral nutrition; EN: enteral nutrition; IASCs: intra-abdominal septic complications.
