The Diagnostic and Prognostic Values of C-Reactive Protein and Procalcitonin during Bacterial Infections in Decompensated Cirrhosis

Table 2

Clinical and laboratory variables associated with infection on admission.

	Bacterial infection group	Nonbacterial infection group	value
Age (yr)			0.509
Male/female	30/30	15/17	0.775
Medical history
Diabetes mellitus	38%	44%	0.614
Hypertension	28%	41%	0.231
Tabagism	28%	19%	0.350
Alcoholism	15%	13%	0.786
Child-Pugh (class)
A	1%	6%	0.123
B	28%	44%	0.256
C	70%	50%	0.456
MELD score			<.001
APACHE II score			0.855
CLIF-SOFA score			0.757
ACLF
Grade 1	32%	38%	0.573
Grade 2	33%	28%	0.609
Grade 3	34%	34%	0.952
Duration of stay (d)			0.766
3-month mortality	34%	3%	0.008
Vital signs
Body temperature (°C)			0.008
Heart rate (beats/min)			0.025
Respiratory rate (breaths/min)			0.189
Systolic blood pressure (mm Hg)			0.393
Diastolic blood pressure (mm Hg)			0.193
Encephalopathy	72%	37%	0.005
Ascite	85%	84%	0.647
WBCs (cells/lL)			0.002
Neutrophil (cells/lL)			0.001
Platelet (cells/lL)			0.361
Serum BUN (mmol/L)			0.282
Serum creatinine (μmol/L)			0.167
AST (IU/L)			0.350
ALT (IU/L)			0.803
Total bilirubin (mg/L)			0.021
PT (%)			0.007
INR			0.005
Albumin (g/L)			0.579
Serum sodium			0.177
CRP (mg/L)			<.001
PCT (ng/mL)			<.001

ALT: alanine aminotransferase; AST: aspartate aminotransferase; CRP: C-reactive protein; PCT: procalcitonin; INR: international normalized ratio; WBC: white blood cell; PT: prothrombin time; MELD: Model for End-Stage Liver Disease; APACHE II: Acute Physiology and Chronic Health Disease Classification System II; BUR: blood urea nitrogen; CLIF-SOFA: chronic liver failure-sequential organ failure assessment; ACLF: Acute-on-chronic liver failure.