Safety of Propofol versus Nonpropofol-Based Sedation in Children Undergoing Gastrointestinal Endoscopy: A Systematic Review and Meta-Analysis

Table 2

Condensed data set. Data was collapsed into the following categories from the raw data, Table 1, using the following criteria; cardiovascular depression included hypotension or bradycardia; respiratory depression included hypoxia, decreased respiratory rate, or apnea.

Study	Group	Cardiovascular depression ()	Respiratory depression ()
Singh et al., 1996	Propofol ()		2
	Propofol + diazemul or pentazocine ()		2
Barbi et al., 2003	Propofol ()	27	8
	Propofol + ketamine ()	17	9
Paspatis et al., 2006	Propofol ()	5	6
	Propofol + midazolam ()	4	4
Hammer et al., 2009	Propofol ()	2	4
	Propofol + dexmedetomidine ()	3	1
Hasanin and Sira, 2014	Propofol ()	0	6
	Dexmedetomidine ()	0	0
Prunty et al., 2015	Propofol ()		3
	Propofol + glycopyrrolate + fentanyl + midazolam ()		17