Clinicopathologic Significance of CXCL12 and CXCR4 Expressions in Patients with Colorectal Cancer

Table 2

Association of expression level of CXCL12 and CXCR4 and clinicopathological characters.

Factor	CXCL12 level	value	CXCR4 level	value
Sex
Men	7.48	0.12	5.76	0.62
Women	12.05		6.60
Age
Younger (≤55 years)	10.29	0.32	6.20	0.86
Older (>55 years)	7.63		5.91
Clinical stage
II	6.87	0.15	5.90	0.83
III	11.46		6.76
IV	13.35		5.34
Locations
Colon	7.78	0.04	5.93	0.71
Rectum	16.36		6.7
Tumour differentiation
Well differentiation	7.58	0.69	17.50	0.43
Moderate differentiation	9.96		16.97
Poor differentiation	9.39		9.83
Angioinvasion
No invasion	11.97	0.24	7.04	0.07
With invasion	7.60		3.72
Lymphatic invasion
No invasion	14.06	0.28	6.27	0.02
With invasion	9.29		4.74
Perineural invasion
No invasion	11.04	0.61	6.27	0.47
With invasion	8.97		4.74
Clinical outcome
Good	8.60	0.78	7.01	0.24
Poor	9.35		5.15