Precursors to Cholangiocarcinoma

Table 2

Classification and characterization of intraductal papillary neoplasms of the bile duct (based on Wan XS, WJG 2013).

	Pancreatobiliary	Intestinal	Gastric	Oncocytic
Histology	Columnar cells with eosinophilic cytoplasm and round nuclei	Stratified columnar cells with goblet cells	Columnar cells resembling gastric foveolae	Cells with abundant eosinophilic cytoplasm
MUC1	+	−	−	Focal +
MUC2	−	+	−	Focal +
MUC5AC	+	+	+	+
CK7	+	+	+	+
CK20	+	+	+	+