Expression of Oncostatin M in Early Gastric Cancer and Precancerous Lesions

Figure 3

Immunohistochemical staining of OSM in different gastric mucosal lesions (OSM shows cytoplasmic staining). Panels (a) to (f) show HE staining sections corresponding to (A) to (F), respectively. Panel (A) shows normal gastric mucosa: OSM expression is negative (bar represents 100 μm). Panel (B) shows intestinal metaplasia gastric mucosa: OSM expression is weakly positive (bar represents 100 μm). Panel (C) shows low-grade intraepithelial neoplasia gastric mucosa: OSM expression is moderately positive (bar represents 100 μm). Panel (D) shows high-grade intraepithelial neoplasia gastric mucosa: OSM expression is strongly positive (bar represents 100 μm). Panel (E) shows early gastric cancer mucosa: OSM expression is strongly positive (bar represents 100 μm). Panel (F) shows advanced gastric cancer mucosa: OSM is moderately positive (bar represents 100 μm).