Research Article

Clinicopathological Characteristics and Prognosis of Upper Gastric Cancer Patients in China: A 32-Year Single-Center Retrospective Clinical Study

Table 1

Clinicopathological characteristics of patients with upper and lower gastric cancer.

Upper gastric cancer (%)Lower gastric cancer (%) value

Sex<0.001
 Male531 (81.8)1098 (70.8)
 Female118 (18.2)453 (29.2)
Age (years)0.003
 <60303 (46.7)833 (53.7)
 ≥60346 (53.3)718 (46.4)
Tumor diameter (cm)<0.001
 <5267 (41.4)946 (61.0)
 ≥5382 (58.9)605 (39.0)
Tissue type0.046
 Well differentiated270 (41.6)575 (37.1)
 Poorly differentiated379 (58.4)976 (62.9)
Tissue growth mode<0.001
 Agglomerate type131 (20.2)434 (28.0)
 Nest type185 (28.0)467 (30.1)
 Diffuse type333 (25.7)650 (41.9)
Macroscopic type
 Early47 (7.2)332 (21.4)<0.001
 Local (Borrmann 1, 2)126 (19.4)212 (13.7)0.068#
 Infiltrative (Borrmann 3, 4)476 (73.4)1007 (64.9)
pT<0.001
 T147 (7.2)331 (21.3)
 T267 (10.3)318 (20.5)
 T3271 (41.8)527 (34.0)
 T4a224 (34.5)340 (21.9)
 T4b40 (6.2)35 (2.3)
pN0.041
 N0232 (35.7)639 (41.2)
 N1116 (17.9)299 (19.3)
 N2138 (21.3)284 (18.3)
 N3a110 (16.9)235 (15.2)
 N3b53 (8.2)94 (6.1)
Lymphovascular tumor embolus0.034
 Positive172 (26.5)346 (22.3)
 Negative477 (73.5)1205 (77.7)
Serosal invasion<0.001
 Positive264 (40.7)375 (24.2)
 Negative385 (59.3)1176 (75.8)
Recurrence and metastasis<0.001
 Positive277 (42.7)526 (33.9)
 Negative372 (57.3)1025 (66.1)

Early versus advanced cancer; #comparison of advanced cancers.