Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice

Figure 4

Baicalin attenuated lithogenic diet-induced damage in liver. (a) HE staining was performed to determine the pathological and physiological characteristics of the liver (the scale bar represented 100 μm). (b, c) The activity of alanine aminotransferase (ALT) (b) and aspartate aminotransferase (AST) (c) in serum. (d–f) The content of inflammatory factors tumor necrosis factor- (TNF-) α (d), interleukin- (IL-) 1β (e), and IL-6 (f) in the liver was detected by ELISA. (g) The malondialdehyde (MDA) content in the liver. (h) The enzymatic activity of superoxide dismutase (SOD) in the liver. (, , and ). ns: no significance; BA(L): 50 mg/kg baicalin; BA(H): 100 mg/kg baicalin.

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