Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice

Figure 5

Baicalin restrained gallstone formation by inhibiting LXRα. (a, b) The representative pictures of gallbladders in mice with lithogenic diet and baicalin or LXRα agonist T0901317 (the arrows indicate the gallbladder). (c) HE staining was performed to detect the pathological and physiological characteristics of the gallbladders of mice in each group (the scale bar represented 100 μm). (d–i) The content of TG (d), TC (e), HDL-C (f), LDL-C (g), and TBA (h) in serum. (i, j) The content of TC (i) and TBA (j) in bile. (, , and ). ns: no significance; BA(H): 100 mg/kg baicalin.

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