Diagnostic Value of Interferon-Gamma Release Assays Combined with Multiple Indicators for Tuberculous Peritonitis
Table 3
Comparison of baseline characteristics and diagnostic value of ROC curves of various combined detection.
Combined detection
AUC
Sensitivity (%)
Specificity (%)
95% CI
PPV (%)
NPV (%)
Two-item in combination
0.804
76.71
77.04
0.745-0.863
64.4
86.0
0.823
90.41
69.63
0.767-0.879
61.7
93.1
0.830
76.71
81.48
0.774-0.886
69.1
86.6
0.844
83.56
78.52
0.789-0.898
67.8
89.8
Three-item in combination
0.816
87.67
68.15
0.759-0.873
59.8
91.1
0.814
90.41
63.70
0.758-0.871
57.4
92.5
0.840
87.67
74.81
0.785-0.894
65.3
91.8
0.823
89.04
71.11
0.767-0.879
62.5
92.3
0.858
95.89
64.44
0.808-0.908
59.3
96.7
0.851
91.78
70.37
0.798-0.904
62.6
94.1
Four-item in combination
0.819
83.56
69.63
0.763-0.875
59.8
88.7
0.857
91.78
69.63
0.807-0.908
62.0
94.0
0.858
83.56
76.30
0.807-0.908
65.6
89.6
0.849
84.93
76.30
0.796-0.901
66.0
90.4
Five-item in combination
0.859
97.26
62.96
0.809-0.909
58.7
97.7
Note: Comparison of AUCs of two-item in combination, ; comparison of AUCs of three-item in combination, ; comparison of AUCs of four-item in combination, . PPV: positive predictive value; NPV: negative predictive value; AUC: area under the curve; QFT: Quanti FERON-TB; ESR: erythrocyte sedimentation rate; ADA: adenosine deaminase; CA125: cancer antigen 125; hs-CRP: high-sensitivity C-reactive protein.
