Combining the Fibrinogen/Albumin Ratio and Systemic Inflammation Response Index Predicts Survival in Resectable Gastric Cancer

Table 3

Univariate and multivariate analysis of OS clinicopathologic variables in relation to OS in resectable gastric cancer patients.

	Univariate analysis		Multivariate analysis
	HR (95% CI)	value	HR (95% CI)	value
Sex
Male	Ref	0.085	Ref	0.939
Female	0.581 (0.313, 1.078)		0.974 (0.494, 1.918)
Age (years)
<60	Ref	0.003	Ref	0.032
≥60	2.979 (1.461, 6.073)		2.313 (1.074, 4.981)
Tumour location
Upper third	Ref		Ref
Middle third	0.697 (0.338, 1.435)	0.327	1.227 (0.584, 2.574)	0.589
Lower third	0.53 (0.281, 0.998)	0.049	0.664 (0.341, 1.294)	0.229
Tumour size (cm)
<3	Ref		Ref
≥3	3.615 (1.773, 7.370)	<0.001	1.295 (0.598, 2.805)	0.512
Differentiation
Poor	Ref		Ref
Moderate and well	0.938 (0.460, 1.913)	0.861	2.209 (1.009, 4.835)	0.048
TNM stage
I	Ref		Ref
II	3.911 (0.831, 18.412)	0.085	2.516 (0.502, 12.602)	0.262
III	17.261 (4.190, 71.105)	<0.001	9.893 (2.029, 48.236)	0.005
FAR-SIRI
0	Ref		Ref
1	2.548 (1.103, 5.890)	0.029	1.229 (0.493, 3.064)	0.658
2	5.760 (3.082, 10.763)	<0.001	2.718 (1.372, 5.386)	0.004