Preventive Effect of Bifidobacterium Supplementation on Neonatal Cholestasis in Preterm Neonates with Very Low Birth Weight

Table 1

Incidence rates of neonatal cholestasis and its associated complications in the study subjects with or without Bifidobacterium supplementation.

	Bifidobacterium group	Control group
Neonatal cholestasis (%)	15 (6.00)	55 (22.00)	26.578	<0.01
Cholestatic liver injury (%)	1 (6.67)	20 (36.36)	4.948	0.029
Septicemia (%)	3 (1.2)	4 (1.6)	0.145	0.725
NEC (%)	2 (0.8)	12 (4.8)	7.349	<0.01
FI (%)	15 (6.0)	30 (12.0)	17.104	<0.01
EUGR (%)	21 (8.4)	37 (14.8)	4.993	0.035

Note: NEC: necrotizing enterocolitis of newborn; FI: feeding intolerance; EUGR: extrauterine growth retardation. The Chi-squared () test was used for comparison of enumeration data of two paired groups. was considered as significant difference between the two groups.