Research Article

Preventive Effect of Bifidobacterium Supplementation on Neonatal Cholestasis in Preterm Neonates with Very Low Birth Weight

Table 3

Comparative analysis of the laboratory tests for the liver function at different time points between the two groups.

Bifidobacterium group ()Control group ()-test

Peak total bilirubin (μmol/L)
 Baseline2.121<0.05
 5 days2.174<0.05
 10 days2.097<0.05
 Discharge from hospital2.592<0.05
Peak direct bilirubin (μmol/L)
 Baseline0.687<0.05
 5 days2.349<0.05
 10 days2.349<0.05
 Discharge from hospital4.149<0.01
Γ-Glutamine transferase (U/L)
 Baseline4.846<0.05
 5 days5.773<0.01
 10 days6.435<0.01
 Discharge from hospital17.97<0.01
Alkaline phosphatase (U/L)
 Baseline9.934<0.01
 5 days3.851<0.01
 10 days9.934<0.01
 Discharge from hospital10.70<0.01
Alkaline phosphatase (U/L)
 Baseline2.024<0.05
 5 days after admission2.000<0.05
 10 days2.530<0.05
 Discharge from hospital2.500<0.05
Total cholesterol (mmol/L)
 Baseline5.972<0.01
 5 days6.638<0.01
 10 days5.928<0.01
 Discharge from hospital4.817<0.01

Note: the independent sample -test was used to compare the means of two sets of data. was considered as significant difference between the two groups.