Are Lumen-Apposing Metal Stents More Effective Than Plastic Stents for the Management of Pancreatic Fluid Collections: An Updated Systematic Review and Meta-analysis

Table 4

Characteristics of studies included comparing LAMS versus plastic stent.

Author, year, country	Design	Groups	N	Age	Male	Type of PFC	Dimensions (cm)	Technical success	Clinical success	Adverse events	DEN
Ge et al. [9], 2017, China	Retrospective	LAMS; Plastic	12; 40	NA; NA	NA; NA	PP; PP	NA; NA	12; 40	12; 40	NA; NA	NA; NA
Lang et al. [14], 2017, USA	Retrospective	LAMS	19	54.6	10	PP 10	10.4	99% (total)	16	4 bleeding, 5 unplanned endoscopy	NA
						WON 9
		Plastic	84	52.2	52	PP 70	8.8		67	8 unplanned endoscopy, 1 perforation, 1 bleeding	NA
						WON 14
Siddiqui et al. [10], 2016, USA	Retrospective	LAMS; Plastic	86; 106	51.5; 56.3	77; 68	WON; WON	11.4; 10.6	84; 105	77; 86	6 bleeding, 1 suprainfection, 3 perforation, 3 stent occlusion, 1 abdominal pain; 2 bleeding, 5 suprainfection, 1 perforation, 23 stent occlusion, 3 migration, 6 other	38; 4
Brimhall et al. [13], 2018, USA	Retrospective	LAMS	97	47	65	PP 16	8.01	90	89	15 bleeding, 2 infection, 6 other	PP 2
						WON 81					WON 11
		Plastic	152	48	98	PP 36	6.98	137	137	5 bleeding, 5 perforation, 6 infection, 6 other	PP 2
						WON 116					WON 31
Bang et al. [26], 2016, USA	Retrospective	LAMS	20	50.7	11	PP 7	12.0	PP 7	PP 7	2 infection, 2 symptomatic migration	NA
						WON 13		WON 13	WON 12
		Plastic	40	52.9	25	PP 14	10.9	PP 14	PP 13	5 infection, 1 symptomatic migration	NA
						WON 26		WON 26	WON 24
Bang et al. [12], 2018, USA	RCT	LAMS; Plastic	31; 29	55.8; 60.3	20; 16	WON; WON	10.2; 10.7	31; 29	29; 28	4 bleeding, 2 buried stent, 3 stricture, 1 migration; 2 migration	4; 6
Shin et al. [31], 2019, Korea	Retrospective	LAMS	10	55.8	8	PP 8	8.28	PP 8	PP 8	1 abdominal pain, 1 pneumoperitoneum	NA
						WON 2		WON 2	WON 2
		Plastic	17	56.4	14	WON 17	7.56	WON 16	WON 15	2 intraprocedural bleeding, 2 pneumoperitoneum
Wang et al. [21], 2019, China	Retrospective	LAMS	70	45.4	52	PP 53	10.9	66	58	NA	NA
						WON 17
		Plastic	62	46.6	36	PP 52	10.3	58	44	NA
						WON 10

LAMS: lumen-apposing metal stents; BFMS: biflanged metal stents; WON: walled-off necrosis; PP: pancreatic pseudocyst; DEN: direct endoscopic necrosectomy; RCT: randomized clinical trial.